For the unfortunate people who have developed End-Stage Kidney Failure (Advanced Kidney Failure), Al-Mustafa Welfare Trust® is providing free dialysis to people who cannot afford dialysis, no matter what cast, creed and religion.
What is Chronic Kidney Disease?
Chronic kidney disease (CKD) is a progressive loss in kidney function over a period of months or years. Each of your kidneys has about a million tiny filters, called nephrons. If nephrons are damaged, they stop working. For a while, healthy nephrons can take on the extra work. But if the damage continues, more and more nephrons shut down. After a certain point, the nephrons that are left cannot filter your blood well enough to keep you healthy.
When kidney function falls below a certain point, it is called kidney failure. Kidney failure affects your whole body, and can make you feel very ill. Untreated kidney failure can be life-threatening.
Some key facts about CKD
How is kidney function measured?
The main indicator of kidney function is your blood level of creatinine, a waste product of the body produced by muscles and excreted by the kidneys. If kidney function is reduced, creatinine accumulates in the blood leading to an elevated level when a blood test is checked.
Kidney function is best measured by an indicator called GFR (Glomerular Filtration Rate) which measures the blood filtration rate by kidneys. This indicator allows doctors to determine if the kidney function is normal, and if not, to what level the reduced kidney function has deteriorated. In everyday practice, GFR can easily be estimated (eGFR), from measurement of the blood creatinine level, and taking into account, age, ethnicity and gender.
Stages of Chronic Kidney Disease (CKD)
Usually, kidney disease starts slowly and silently, and progresses over a number of years. Not everyone progresses from Stage 1 to Stage 5. Stage 5 is also known as End-Stage Renal Disease (ESRD).
GFR: Glomerular Filtration Rate
CGA: Cause, GFR and Albuminuria categories
Source: “KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease
Causes of CKD
High blood pressure (hypertension) and diabetes are the most common causes of kidney disease. The high blood pressure causes just over a quarter of all cases of kidney failure. Diabetes has been established as the cause of around one-third of all cases and is the commonest cause of ESRD in most developed countries.
Other less common conditions include inflammation (glomerulonephritis) or infections (pyelonephritis).
Sometimes CKD is inherited (such as polycystic disease) or the result of longstanding blockage to the urinary system (such as enlarged prostate or kidney stones).
Consultant Nephrologist and Head of Nephrology Department, Shifa International Hospital (SIH), Dr. Farhat Abbas advises that consuming junk and low quality food, self-medication and excessive use of medicine (pain-killing drugs if taken over a long time), low water intake, obesity, diabetes and renal stones can also cause kidney disease. Consultant Nephrologist Khawaja Sayeed Ahmed said Pakistan is at number eight in the world in kidney diseases. He said toxic drugs and fake medicines have their own considerable share in kidney damage.
However, in certain patients these conditions may not be the case and therefore some doctors may be unable to determine what caused the disease to appear.
There is no cure for chronic kidney disease, although treatment can slow or halt the progression of the disease and can prevent other serious conditions developing.
The main treatments are a proper diet and medications, and for those who reach ESRD, long term dialysis treatment or kidney transplantation. In the early stages of kidney disease, a proper diet and medications may help to maintain the critical balances in the body that your kidneys would normally control. Consultant Nutritionist Dr. Rezzan Khan said that to avoid kidney disease diet, nutrition and lifestyle should be healthy throughout the life even if diabetes or blood pressure is under control.
However, when you have kidney failure, wastes and fluids accumulate in your body and you need dialysis treatments to remove these wastes and excess fluid from your blood, dialysis can be done either by machine (hemodialysis) or by using fluid in your abdomen (peritoneal dialysis). In suitable patients a kidney transplant combined with medications and a healthy diet can restore normal kidney function.
Dialysis is the process of cleansing the blood of harmful waste products, and poisonous substances by passing it through a special machine. Dialysis is necessary when the kidneys function has deteriorated to an extent (Stage V of Kidney Failure) when treatment by medicines and diet does not help. The earlier stages of kidney failure (Stages I- IV) can be managed with conservative treatment (medicines and diet). When the patients reaches Stage V of Kidney Failure the only options he has are dialysis and kidney transplant. Delaying dialysis at that stage can have deleterious effects, even death.
There are two types of dialysis: hemodialysis and peritoneal dialysis.
In hemodialysis, your blood is pumped through a dialysis machine to remove waste products and excess fluids. You are connected to the dialysis machine through a needle in a vein that is surgically enlarged (vascular access) or through a temporary plastic catheter placed in a vein. This allows blood to be removed from the body, circulate through the dialysis machine for cleansing, and then return to the body. Hemodialysis can be done at a dialysis center or at home. When done in a center, it is generally done three times a week and takes between three and five hours per session. Home dialysis is generally done three to seven times per week and takes between three and ten hours per session (often while sleeping).
Peritoneal dialysis is another form of dialysis used to remove waste products and excess water. It works on the same principle as hemodialysis, but your blood is cleaned while still inside your body rather than in a machine by adding clean fluid to your abdomen, letting it accumulate waste products from the blood and then draining it out. It is typically done at home. Some patients can perform peritoneal dialysis continuously while going about normal daily activities (continuous ambulatory peritoneal dialysis, CAPD).
The dialysis machine for all practical purposes performs the same function that human kidneys perform. The process of dialysis or the flushing out of the kidneys of toxic material is not a one-time function. It has to be performed at least twice a week or ideally thrice a week. The dialysis machine does not cure the disease, it only performs the function of the kidneys which are not functioning.
A kidney transplant is an operation to place a healthy (donor) kidney in your body to perform the functions your own diseased kidneys can no longer perform.
Kidney transplantation is considered the best treatment for many people with severe CKD because quality of life and survival are often better than in people who use dialysis. However, there is a shortage of organs available for donation. Many people who are candidates for kidney transplantation are put on a transplant waiting list and require dialysis until an organ is available.
A kidney can come from a living relative, a living unrelated person, or from a person who has died (deceased or cadaver donor); only one kidney is required to survive. In general, organs from living donors function better and for longer periods of time than those from donors who are deceased.
Overall, transplant success rates are very good. Transplants from deceased donors have an 85 to 90% success rate for the first year. That means that after one year, 85 to 90 out of every 100 transplanted kidneys are still functioning. Live donor transplants have a 90 to 95% success rate. Long-term success is good for people of all ages.
Some Key Statistics
AMWT® Free Dialysis
At our main hospital (Gulshan-e-Iqbal), we are providing Free Dialysis facilities to those patients who simply cannot afford the medical costs. The harsh reality for those people that require kidney dialysis is that they can die if they don’t get medical treatment every week and sometimes even twice a week, depending on the severity of the patient’s condition.
The centre gives special preference to young patients that will be ideal candidates for kidney transplant, as well as male members, who are bread-earners for the entire family.
New Dialysis Centre Development Appeal
Due to the heavy burden on our current dialysis centre in Gulshan-e-Iqbal, we are planning to open 5 more Kidney Dialysis centres in Pakistan in the next 12 months. These centres are not only vital but they can help save thousands of lives, so please help Al-Mustafa Welfare Trust® to find the financial resources to build these Dialysis Centres so that we can prevent thousands of patients from dying of end-stage kidney failure.
Our Kidney Dialysis campaign hashtag on facebook, google+, instagram, flickr and twitter is: #kidneydialysis
How your donations can help
Make your Monthly or One-Off Donation
To make a monthly donation simply choose the monthly amount from the drop down list, click “add to cart” then you will be directed to your shopping cart page where you can view/amend your cart and then click “proceed to checkout”. If you wish to enter your own amount then choose “Other” from the Amount dropdown list.
Kidney Dialysis Monthly Donation
To make a one-time donation simply choose the amount from the drop down list, click “add to cart” then you will be directed to your shopping cart page where you can view/amend your cart and then click “proceed to checkout”. If you wish to enter your own amount then choose “Other” from the Amount dropdown list.
Kidney Dialysis One-Off Donation
Kidney Disease in the News
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DYLS10 £10 to 70070 to make a ten pound donation towards providing Dialysis Treatment
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Chronic Kidney Disease in Pakistan Article
Chronic Kidney Disease Update
Waqar H. Kazmi and Khurram Danial Karachi Medical & Dental College, Abbasi Shaheed Hospital, Karachi Pakistan